The mutated strain’s effects are more severe, and it is more transmissible — but drugs are still effective against it.
, serve as a reminder that viruses do not always evolve to become less virulent over time. Reports that infections with the Omicron variant of SARS-CoV-2 tend to cause mild COVID-19 symptoms have fuelled the narrative that the virus is becoming less deadly. “This is not how it works,” says Emma Hodcroft, a molecular epidemiologist at the University of Bern. Although HIV and SARS-CoV-2 are different in many ways, “it’s not a given that SARS-CoV-2 will become milder”, Hodcroft says.
The researchers estimate that, without treatment, people infected with this variant would develop AIDS within 2–3 years after diagnosis, compared with 6–7 years for those infected with other HIV strains.Using genome sequences, the researchers traced evolutionary relationships between HIV variants to determine how fast the virus had spread.
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