Human eyes are the only natural window we have into a person's central nervous system.
program, researchers compared the eye scans of 154,830 patients aged 40 years and over.
The 700 individuals in this group with prevalent Parkinson's disease showed a small but significant difference in the look of their retinas. In certain regions, they noticed a thinning in the layer of inner ganglion cells, which are a type of neuron that transmit visual information via dopamine. Researchers then used this information in their examination of eye scans from 67,311 people in the UK Biobank database, 53 of whom were diagnosed with Parkinson's during the study.
They found that this thinning of the inner ganglion layer can appear in the early stages of Parkinson's, even before clinical symptoms show up.of ganglion thinning in individuals with Parkinson's and add weight to the idea that the eyes show some of the first outward signs of the disease. Currently, one of the trickiest parts of diagnosing and treating Parkinson's disease is that its symptoms lag far behind its pathology.
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