Using MRI as a screening test alongside PSA density allowed detection of cancers that would have been missed by the blood test alone, according to new research.
, is the first study to use MRI scans with prostate specific antigen density to assess the need for further standard NHS tests. Of the 29 participants found to have serious prostate cancer, 15 had a 'low' PSA score that would have meant they were not referred for further investigation under the current system.
In recent years, the introduction of MRI as a first step in investigating men at higher risk of prostate cancer has spared one in four men from an unnecessary biopsy, which is invasive and can lead to complications. After NHS assessment, 29 men were diagnosed with cancer that required treatment, 15 of whom had serious cancer and a PSA of less than 3ng/ml. Three men were diagnosed with low-risk cancer that did not require treatment.
The next step towards a national prostate cancer screening programme is already underway, with the LIMIT trial being conducted with a much larger number of participants. The trial will also attempt to recruit more black men, including through mobile 'scan in a van' initiatives designed to visit communities less likely to come forward for testing in response to a GP invitation.
France Dernières Nouvelles, France Actualités
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