Exploring taste and smell dysfunction as strong predictors of SARS-CoV-2 infections ColumbiaMed Taste Smell Dysfunction COVID19 SARSCoV2 Infection
By Pooja Toshniwal PahariaDec 16 2022Reviewed by Aimee Molineux In a recent study published in PLoS ONE, researchers investigated whether coronavirus disease 2019 -associated chemosensory alterations were predictive of serological responses against severe acute respiratory syndrome coronavirus 2 among United States residents.
The study was conducted between April and June 2020 on 306 adult COVID-19 convalescent individuals who volunteered for blood donation following perceived SARS-CoV-2 infection. The individuals were enrolled for CPT at the Irving medical center of the NewYork-Presbyterian/Columbia university following a recent history of COVID-19.
The team excluded individuals who had received antiviral therapy within 24.0 hours of blood donation, needed extracorporeal membrane oxygenation or mechanical ventilation for ≥5.0 days, had severe multiorgan dysfunction, pregnancy, IgA deficiency, or prior history of allergy reactions after blood transfusions.
Prior to data adjustments, the odds of developing suprathreshold IgG titers were 2.0-fold greater among individuals who documented smell alterations and 2.02-fold greater among individuals who documented taste alterations in comparison to individuals with normal taste and smell.
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