Science, Space and Technology News 2024
Dr. Or Shemesh has received a $400,000 NIH award to create a new platform for treating brain disorders by modifying glial cells with bioengineered RNAs, offering a promising approach to combat diseases like Alzheimer’s without the immune risks associated with viral vectors.
The project aims to genetically modify different types of glia, a class of cells that supports and protects the brain’s neurons. “Glia cells are pivotal to the development of brain disease, so approaches that alter their activity could lead to new treatments,” says Shemesh, assistant professor of neurobiology at Pitt’s School of Medicine.-based vectors to deliver genes to neurons.
“We are seeing more research, including from Pitt, that indicates astrocytes and other glia play an important role in the development ofdisease,” Shemesh says. “So our new platform could one day provide a unique strategy to treat dementia.”SciTechDaily: Home of the best science and technology news since 1998. Keep up with the latest scitech news via email or social media.
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