Could adhering to a healthy lifestyle decrease the risk of post–COVID-19 condition? HarvardChanSPH HealthyLifestyle PostCOVID COVID19 SARSCoV2 Risk
By Neha MathurFeb 8 2023Reviewed by Aimee Molineux In a recent study published in JAMA Internal Medicine, researchers performed a prospective cohort study among 1981 female nurses to investigate whether maintaining a healthy lifestyle decreases the risk of post–coronavirus disease 2019 condition following severe acute respiratory syndrome coronavirus 2 infection.
About the study In the present study, researchers administered seven sequential surveys between April 2020 and November 2021 to identify female nurses with confirmed SARS-CoV-2 infection and PCC characterized by a minimum of four weeks of symptoms. Additionally, they explored whether a preinfection healthy lifestyle was associated with fewer PCC symptoms.
Related StoriesThe team used Poisson regression to estimate PCC relative risk correlated with six healthy lifestyle habits. Also, they calculated the population attributable risk percentage that denoted the proportion of PCC cases that hypothetically would not have occurred if all participants were in the low-risk group. Finally, they conducted ten sensitivity analyses.
First, all six unhealthy lifestyle choices increase the risk of chronic inflammation that might have predisposed affected individuals to excessive release of cytokines after infection. Together, this increased the risk of long-term complications in multiple organs. Second, these habits might have disturbed adaptive autoimmunity, as seen in PCC-affected individuals.
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