Worsening Depression Can Precede Stroke in Older Adults

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Worsening Depression Can Precede Stroke in Older Adults
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Depression starts to worsen in the months or years before stroke occurs, suggests a new study.

Pre- and Post-Stroke Depression

To investigate, Blöchl and colleagues identified the trajectory of depressive symptoms several years before and after incident stroke in 10,797 adults from theThe 425 case participants who experienced an incident stroke during a 12-year follow-up period were propensity-score matched with 4249 stroke-free individuals.

Starting about 2 years before stroke onset, the severity of depressive symptoms increased by an average of 0.33 points , with a further increase of 0.23 points after stroke . Depressive symptoms remained elevated for 10 years after stroke. There was no statistically significant difference in prevalence of probable depression at the 2-year pre-stroke assessment among those with and without stroke . At the time of stroke, however, probable depression was significantly more common in the stroke group , a difference that persisted at the 6-year assessment.

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