The real danger comes from when such animals are herded together in close quarters, giving pathogens access to a bigger pool of individuals in which to mutate
, an order of meat-eating mammals that includes cats, dogs, bears and mink, among others.is a potent source of “zoonotic” diseases—those that have jumped to humans from their original animal hosts. Almost half of its members carry one or more unique zoonotic pathogens. Biologists have long wondered why that should be. Dr Bryant’s paper, published inDiseases jump from animals to humans when a pathogen stumbles upon a mutation that allows it to infect human cells as well as animal ones.
While Dr Bryant’s team looked only at dogs, the mutations resemble those found in other sorts of carnivorous mammal, including cats, ferrets and bears. All share the fusion in the effector genes, though the specific faults with their receptors differ. That suggests similar defects have evolved several times in different lineages.
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