In June 2000, two rival groups of researchers shook hands in the shared success of a milestone in biology – the delivery of a rough draft of the human genome.
Unfortunately, reading it is easier said than done. Not only is the sheer mass of data a problem, subtle differences in samples, diverse formats, and analysis techniques prioritizing different kinds of errors all present obstacles to a unified interpretation.
The tree's branches comprise of a mind-blowing 231 million ancestral lineages. At its base is a spread of roots represented by eight ancient, highly detailed human genome sequences, with thousands of smaller snippets used to confirm their place deep in our past.genomes, one genome from a Denisovan, and a small family who lived in Siberia more than four thousand years ago.
Their tree sequence method makes use of what's known as a succinct data structure – a computing concept that aims to represent data in an optimal amount of space that also limits the amount of time needed to probe it all with questions. In this specific case, a tree sequence finds correlations between different branches of a tree to help make the large pools of information easier to study.
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