Watch an exclusive 1st clip of Oprah Winfrey's special on drugs used for weight loss

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Watch an exclusive 1st clip of Oprah Winfrey's special on drugs used for weight loss
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Winfrey revealed in December that she takes a prescription drug for weight loss.

Winfrey sat down with medical experts, including ABC News chief medical correspondent and obesity medicine physician Dr. Jen Ashton, and everyday people using, "An Oprah Special: Shame, Blame and the Weight Loss Revolution," airing Monday at 8 p.m. EDT/7 p.m. CDT, on ABC.

"The number one thing I hope people come away with is knowing that is a disease, and it's in the brain," Winfrey said in the clip, which aired Monday on "that she uses a medication to help maintain her weight after losing weight steadily over the past two years with a combination of diet and exercise..

Both Ozempic and Mounjaro are approved by the U.S. Food and Drug Administration to treat Type 2 diabetes, but some doctors prescribe the medication "off-label" for weight loss, as is permissible by the FDA.In November, the FDA approved Zepbound as a weight loss management treatment for people with obesity, or those who are overweight with at least one related underlying condition, such as high blood pressure -- the same prescribing guidance as Wegovy.

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