Cleveland Police are reinvestigating the murder of Vicky Glass, last seen in Middlesbrough in 2000.
A lorry driver seen with a woman before she disappeared more than 20 years ago may have information about her murder, detectives say.
Officers - who are keen to speak to the lorry driver - describe him as white, aged in his mid-30s at the time, with a broad build and a distinctive mole on his face. "Vicky did not have access to a car and wasn't known to frequent or have any association to Danby therefore the inquiries being undertaken are crucial and we ask the residents to help if they can," he said.
In a statement they said: "As a family we have been through turmoil, especially as mam Deborah passed away without any answers, knowing Vicky's killer is out there and people have information that they are not coming forward with."
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