Research from the UC Davis MIND Institute sheds light on maternal autoantibody-related autism A neurodevelopmental condition called autism spectrum disorder affects 1 in 44 kids in the United States. It has a broad range of characteristics with various intensities and origins. Maternal autoantibody
Autism spectrum disorder is a neurological and developmental condition. The condition affects how people interact, communicate, learn, and behave with others.A neurodevelopmental condition called autism spectrum disorder affects 1 in 44 kids in the United States. It has a broad range of characteristics with various intensities and origins. Maternal autoantibody-related autism spectrum disorder is one kind of autism.
It found reactivity to at least one of the nine MAR ASD patterns in 10% of the autistic group. This is compared with 4% of the intellectual disability group for some patterns, and 1% of the general population group. Four patterns were present only in mothers whose children were later diagnosed with autism, making those particular autoantibody patterns highly predictive.
A team of researchers led by Kathleen Angkustsiri explored MAR ASD in two new clinical sites: the Children’s Hospital of Philadelphia and Arkansas Children’s Hospital and Research Institute . Their study, published in, recruited 68 mothers of autistic children ages 2-12 years. The mothers provided blood samples and completed behavioral questionnaires about their children.The study also included data from the children’s clinical diagnostic assessments.
“MAR ASD positivity may be linked to more severe autism behaviors,” Angkustsiri said. “Both the SCQ reported by parents and the ADOS assessed by clinicians supported these findings.”
France Dernières Nouvelles, France Actualités
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