Really, we should envy spiders.
Oil droplets of either one of these proteins form in humans when they become entangled, like boiled spaghetti on a plate. At first, the proteins are flexible and elastic, much like spidroin oil droplets.
To our surprise, we saw that the spidroin proteins, which normally form pairs, instead split into single molecules. The end part of the spidroin, called c-terminal domain, makes it form pairs. The c-terminal also startsSo, we made a spidroin which contained only the c-terminal domain and tested its ability to form fibers.
This makes sense since the spidroin molecules must find each other when forming a fiber. Entangling the spidroins like spaghetti helps them rapidly assemble into silk.
France Dernières Nouvelles, France Actualités
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