There's still much to learn about cognitive health.
This study found that both the Alzheimer's patients and people with early signs of Alzheimer's showed an increase in PHGDH, compared to the subjects with. Not only that, but the Alzheimer's patients' PHGDH levels became even higher as their condition worsened, and researchers equated these high PHGDH results to overstimulation within the brain caused by too much serine.
An extreme amount of stress on the brain can lead to a decreased number of neurons in the brain, and researchers believe that aoccurs to make up for the loss in brain activity. The body continues to create more and more PHGDH to increase serine levels and healthy brain cells. Unfortunately, when there is too much PHGDH in the brain, there is too much stress on the brain, and neurons/brain cells continue to die. The cycle repeats due to the brain trying to restore balance.
Other studies and clinical trials have found L-serine to be a neuroprotective agent for a number of other neurological diseases and conditions , according to. The supplement has been seen to have a therapeutic effect on epilepsy, schizophrenia, and psychosis. Overall, if you're looking into supplementation to accommodate concerns regarding your future brain functionality and the possibility of developing Alzheimer's disease, talk with your doctor. Research has fallen on both sides of the spectrum for whether or not it's necessary or productive to feed your brain these compounds that your body forms naturally if there isn't already an imbalance.
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