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Ever feel like everything hurts after not getting enough sleep? A new study reveals a neurotransmitter involved in the pain that sleep deprivation causes, indicating a potential new target for treatment.
Mice that underwent five consecutive days of sleep deprivation showed higher sensitivity in tests designed to measure response to pain. Brain signal measurements showed exaggerated activation of specific neurons in the TRN that project to an area of theLooking at brain metabolites, the researchers discovered that the endocannabinoid NADA levels were lower in the TRN of mice that had not slept enough compared to control mice. This drop was only seen in the TRN.
France Dernières Nouvelles, France Actualités
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