A misunderstanding about the microbe that actually causes the flu created a ripple effect that changed the future of U.S. drug development, clinical trials, and pandemic preparedness
muzzle to muzzle
Flu deaths finally returned to pre-pandemic levels in 1921, and for the next nine years scientists tried—and failed—to definitively rule out Pfeiffer’sas the causative agent, in part because seasonal flu continued to ravage communities who had no effective treatments.
They were right. It had taken roughly 40 years, thousands of studies, and tens of millions of deaths, but scientists had finally found the real cause of pandemic influenza. A full 72 years later, in 2005, Taubenberger and his colleagues were able tothat caused the 1918 pandemic using tissues from a woman preserved in Alaskan permafrost. It was H1N1, and it had leapt from birds to humans.
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