Successful New First in Chronic Heart Failure Treatment Using Cell Therapy

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Successful New First in Chronic Heart Failure Treatment Using Cell Therapy
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New cell therapy offers potential treatment option for patients with chronic heart failure. Physician-scientists at The Texas Heart Institute announced today the results of the largest cell therapy trial to date in patients with chronic heart failure due to low ejection fraction. The therapy bene

Physician-scientists at The Texas Heart Institute announced today the results of the largest cell therapy trial in patients with heart failure to date. The therapy benefited patients by reducing the risk of heart attack and stroke and improving the heart’s ejection fraction, especially in patients who have high levels of inflammation. The findings are published in the Journal of the American College of Cardiology. Credit: © Copyright Texas Heart Institute. All rights reserved.

These activated pathways eventually contribute to the progression of heart failure and repeated hospitalizations. Despite advances in therapies targeting these pathways, mortality rates remain high. The unique mechanism of action of MPC appears to provide an alternative approach that has the potential to make a significant impact on the high mortality of this disease.

Investigators in the landmark clinical trial, Dream-HF have shown that cardiac stem cell therapy may provide additional benefits to drug therapy by treating, for the first time, a major contributor to heart failure—inflammation. Credit: © Copyright Texas Heart Institute The Texas Heart Institute’s Emerson Perin, MD, PhD published findings of the largest cell therapy trial in patients with heart failure to date. The therapy benefited patients by reducing the risk of heart attack and stroke and improving the heart’s ejection fraction, especially in patients who have high levels of inflammation. Credit: © Copyright Texas Heart Institute

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