An observational study of 96,000 hospitalized COVID-19 patients shows that those who were treated with hydroxychloroquine were likelier to die
Hydroxychloroquine has been used to treat COVID-19 patients. A new study suggests that’s a bad idea. Photo: Soumyabrata Roy/NurPhoto via Getty Images A new observational study conducted on the effect of hydroxychloroquine and chloroquine on COVID-19 patients found that the medications provide no benefit and are actually “associated with an increased risk of in-hospital mortality.” The study, which is the largest of its kind conducted on the drugs, was published in The Lancet Friday.
For the study, researchers reviewed the cases of just over 96,000 patients treated for COVID-19 in 671 hospitals across six continents. Close to 15,000 of them were treated with hydroxychloroquine or chloroquine, which have both been used to treat malaria and autoimmune disorders for years. Some patients received one of the drugs by itself. Some took an antibiotic, too.About 1 in 11 patients in the control group died in the hospital.
Still, the researchers have seen enough to feel confident that the drugs are not an effective treatment for COVID-19. “Justification for repurposing these medicines in this way is based on a small number of anecdotal experiences that suggest they may have beneficial effects for people infected with the SARS-CoV-2 virus,” Frank Ruschitzka, a co-author of the study, said in a statement.
The physician Eric Topol, speaking to the Washington Post, provided an even more stark assessment: “It’s one thing not to have benefit, but this shows distinct harm. If there was ever was hope for this drug, this is the death of it.”
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