Sense of smell most often diminishes by the third day of infection with COVID-19, and many patients also lose their sense of taste at the same time, according to a new study.
The findings may help identify patients most likely to benefit from antiviral treatment, according to the researchers.
"The relationship between decreased sense of smell and the rest of the COVID-19 is something to be aware of. If someone has a decreased sense of smell with COVID-19, we know they are within the first week of the disease course and there is still another week or two to expect," said principal investigator Dr. Ahmad Sedaghat of the University of Cincinnati College of Medicine.
His team examined characteristics and symptoms of 103 patients in Switzerland who were diagnosed with COVID-19 over six weeks. The patients were asked how many days they had COVID-19 symptoms and also about the timing and severity of lost or reduced sense of smell, along with other symptoms. At least 61% of the patients reported reduced or lost sense of smell, and the average onset for this was 3.4 days, according to the study. The findings were published online recently in the journalProblems with sense of smell were more likely to occur in younger patients and women.
"We also found in this study that the severity of the loss of smell is correlated with how bad your other COVID-19 symptoms will be," Sedaghat said in a university news release. He's an associate professor of otolaryngology-head and neck surgery.
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