Science’s 2021 Breakthrough of the Year: AI brings protein structures to all

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Science’s 2021 Breakthrough of the Year: AI brings protein structures to all
France Dernières Nouvelles,France Actualités
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AI-powered protein structure predictions, which was chosen as Science’s 2021 Breakthrough of the Year, will forever change biology and medicine. Learn more: BOTY

MULTIDISCIPLINARY ASSOCIATION FOR PSYCHEDELIC STUDIES

: A multicenter, randomized, controlled trial found that 3,4-methylenedioxymethamphetamine , popularly called ecstasy, significantly reduced symptoms in patients with post-traumatic stress disorder .in May, tested an intensive combination of talk therapy and MDMA, which can create a sense of well-being and empathy that may help people process traumatic experiences.

and other life-threatening pathogens, including respiratory syncytial virus , HIV, and malaria parasites.. As medicines, they are mostly used to tamp down immune responses or mark tumor cells for destruction. The only mAbs approved for infectious diseases in the United States are limited to rare maladies: Ebola, inhalational anthrax, recurrent, RSV in high-risk infants, and HIV in people for whom all drugs have failed. India has approved a mAb for rabies.

Monoclonals are also being developed against influenza, Zika, and cytomegalovirus. High hopes surround two candidates designed to prevent RSV in all infants. And in one HIV prevention study that failed overall, the candidateHigh costs and the need to infuse mAbs in a clinic have put them out of reach for many.

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