Researchers identify novel genes that may increase risk for schizophrenia mountsinainyc NatureGenet
recent study
"By focusing on a subset of genes, we discovered rare damaging variants that could potentially lead to new medicines for schizophrenia," said lead author Dongjing Liu, Ph.D., a former postdoctoral researcher in the laboratory of Alexander W. Charney, MD, Ph.D., a co-senior corresponding author of the study and Associate Professor of Psychiatry, Genetics and Genomic Sciences, Neuroscience, and Neurosurgery, at Icahn Mount Sinai.
previously established in predominantly white people have now been extended to non-whites for this debilitating disease."was previously implicated in schizophrenia but is now identified as having a shared risk for schizophrenia and autism. That finding raises a question about how we think about brain diseases as a whole, suggested Dr. Charney.
The researchers caution that not every patient has a rare damaging variant in the identified schizophrenia genes. The disease is multifactorial and there is no single factor.
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