Even if the causes of long COVID remain confusing, researchers are zeroing in on biomarkers – compounds that can be detected and measured – that can help them better diagnose and treat the condition.
The rise of ever new COVID variants has complicated research. Much of the early research was done before the rise of the Omicron variant. Walt said he found spike protein in fewer Omicron long COVID samples – closer to 50% than 65% – and researchers have found fewer clots in Omicron patients,Like some of the other scientists focused on long COVID, Mohamed Abdel-Mohsen, PhD, started out looking at another virus, in his case HIV.
“There are many steps to interfere therapeutically and hopefully decrease symptoms and enhance the quality of people experiencing ,” he says. While research looking at biomarkers is in its early stages, the hope is to find a biomarker that points to a treatment.he holy grail of biomarkers are really surrogate markers,” Peluso said during November’s RECOVER briefing. “What a surrogate marker means is you identify the marker, you identify the level of the marker, and then you do something to change that. And changing the level of the biomarker results in a change in the clinical outcome.
In other words, something similar to a statin drug, which lowers levels of bad cholesterol – something that, in turn lowers stroke and heart attack rates.David Walt, PhD, co-director, Mass General Brigham Center for COVID Innovation, Boston.
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