Recent surge in group A streptococcal infections among children in UK

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Recent surge in group A streptococcal infections among children in UK
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Recent surge in group A streptococcal infections among children in UK Children Streptococcus Infections Guidelines Europe UK France

Study: Group a streptococcal infections amongst children in Europe: taming the rising tide. Image Credit: MyFavoriteTime / Shutterstock

The average case fatality ratio has been estimated to be 10%. The highest ratio has been observed among children aged 10-14 years, followed by older adults aged 75 years and above. According to the World Health Organization report, more than 18 million people worldwide are affected by group A strep infections. In addition, an annual induction in cases and mortality has been estimated to be more than 1.7 million and 500,000, respectively.

Therapeutic and preventive interventions Antibiotic therapy with penicillin is considered the gold standard for group A strep infections. Amoxicillin, macrolides, cefalexin, and co-trimoxazole are potent antibiotics in people with penicillin allergy or intolerance. Considering clinical presentations, the authorities have recommended a shorter 5-day antibiotic course for children with symptomatic infection. Children can remain contagious for 10-21 days if not treated. However, contagious infections mostly resolve after 24-48 hours of the initiation of antibiotic therapy.

As Professor Shiranee Sriskandan of the Imperial College London’s Centre for Bacterial Resistance Biology mentioned, a rapid expansion and dominance of bacterial strains with better evolutionary fitness than previously circulating strains could be the reason behind this sudden surge in cases.

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