Inspired by the record-fast creation of mRNA vaccines that blunted the impact of COVID19, a philanthropist is providing 250 million Australian dollars (U.S. $172 million) over 20 years to try the same with therapeutics during future pandemic threats.
Inspired by the record-fast creation of messenger RNA vaccines that blunted the impact of COVID-19, a philanthropist is providing AU$250 million over 20 years to try the same with therapeutics during future pandemic threats. The donation will fund a research center in Melbourne that will develop technologies to quickly create antiviral treatments such as monoclonal antibodies when new infectious diseases emerge.
Angus introduced Cumming, a Canadian and New Zealand citizen living in Melbourne, to infectious diseases researcher Sharon Lewin, head of the University of Melbourne’s Peter Doherty Institute for Infection and Immunity. Over a series of meetings, Lewin pitched the idea of working on antiviral treatments. “Most people don’t really understand what therapeutics [can do] in a pandemic,” says Lewin, who will head the new center.
The center will go beyond the current staple of antivirals, a class of drugs known as small molecules, Lewin says. Three areas of initial focus will be improving monoclonal antibodies that neutralize viruses; targeting viral RNA rather than a pathogen’s proteins; and shoring up the human immune system’s own antiviral actions. The center will partner with industry to commercialize products and will not conduct clinical trials itself.
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