Paul Berg, the Nobel Prize-winning biochemist whose ground-breaking experiments in gene-splicing reshaped cancer research and helped spawn the multibillion-dollar biotechnology industry, has died. He was 96.
Paul Berg, the Nobel Prize-winning biochemist whose ground-breaking experiments in gene-splicing reshaped cancer research and helped spawn the multibillion-dollar biotechnology industry, has died at his home on the Stanford University campus.
An example was his realization that the genetic engineering technique he pioneered could be used to spread super-pathogens around the world. In response, Berg halted his own research and helped draft a moratorium on gene editing in the 1970s. Paul Berg was born June 30, 1926, in Brooklyn, the eldest of three sons of Harry and Sarah Brodsky Berg. After emigrating from Russia, Berg’s father started a business manufacturing fur hats and coats, but was never successful. Family circumstances were “modest to poor,” Berg recalled.
“If I can bring my entire department, I will come,” Kornberg said, according to Berg. “Be our guest. Bring your crew,” was Stanford’s response. He stopped his own research and called for an international conference to discuss the “potential biohazards of recombinant DNA molecules.” The now-famous conference at Asilomar in Pacific Grove, Calif., in 1975 brought together 100 scientists from 16 countries, resulting in a temporary moratorium on gene-editing until the process could be proved safe.
One of those ways was his refusal to use his newfound biotechnology wealth to buy the kind of opulent home that appealed to other Silicon Valley innovators. He continued to live with his wife, Mildred, in the simple house on campus he bought for $25,000. His one indulgence was modern art, particularly pieces by Robert Motherwell and Sam Francis.
President George W. Bush restricted the use of federal funds in stem cell research after several religious groups protested that a days-old embryo was a human life.
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