Domperidone, which blocks dopamine in the brain, is approved in Canada as an aid to speed up digestion, but it also has a side effect: lactation.
Domperidone, which blocks dopamine receptors in the brain, is approved in Canada as an aid to speed up digestion, but it also has a side effect: lactation. The College of Physicians and Surgeons of Ontario has expressed concern about the prescribing and oversight practices of a Toronto breastfeeding doctor in a case where a woman was prescribed domperidone, whose off-label use to induce lactation is controversial.
"The Respondent did not meet the standard of care of a breastfeeding medicine physician practicing in the Province of Ontario," the assessor wrote in a complaint decision issued by the College Feb. 28, 2024 and obtained by CBC News. of two women who suffered severe psychological withdrawal effects when they stopped taking the drug abruptly, symptoms they say they were not warned about. One of those women – a resident of the U.S., where domperidone is not authorized for any purpose – was prescribed by Newman.WATCH | Women report alarming withdrawal effects after stopping domperidone:DurationWARNING: This story contains distressing details about suicidal thoughts and attempts.
At the time, there was also less known about the psychological withdrawal effects of the medication, the college stated.The CurrentThen, many new mothers have been prescribed the drug Domperidone to help with breastfeeding, but no country has approved the drug as a lactation aid. We hear about a CBC investigation into those prescriptions — and the alarming side effects many women are reporting.
"I was having suicidal ideation. I couldn't sleep. I was extremely anxious. I was having panic attacks. I was terrified to tell people exactly what was going on because I didn't want them to take my children away from me. And so what I ended up doing was I said to my husband, you can't leave me alone with these kids," she recalled.
In 2022, pregnant with her third child, McCabe said she saw a perinatal psychiatrist who told her she did not have bipolar disorder and that her initial symptoms had been caused by domperidone withdrawal. But McCabe said she didn't truly believe that until later that year, when she listened to the stories of other women who had experienced it in the CBC coverage.
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