New study ties weight-loss drugs Wegovy, Ozempic to serious gastrointestinal conditions

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New study ties weight-loss drugs Wegovy, Ozempic to serious gastrointestinal conditions
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A pharmacist displays boxes of Ozempic, a semaglutide injection drug used for treating type 2 diabetes made by Novo Nordisk, at Rock Canyon Pharmacy in Provo, Utah, U.S. March 29, 2023.

Medicines in the same class as popular weight-loss therapies Ozempic and Wegovy may carry an increased risk of pancreatitis, intestinal blockage and stomach paralysis compared to an older obesity drug, Canadian researchers find.A pharmacist displays boxes of Ozempic, a semaglutide injection drug used for treating Type 2 diabetes made by Novo Nordisk.

Nearly five in every 1,000 users of semaglutide drugs developed pancreatitis, compared to one of every 1,000 users of bupropion-naltrexone, the active ingredients in the weight-loss drug Contrave, according to a report in thePancreatitis, or inflammation of the pancreas, can cause severe abdominal pain.

Mahyar Etminan, an epidemiologist at the University of British Columbia and senior author of the study, said up to two per cent of patients who used semaglutide and liraglutide medications to lose weight developed gastrointestinal problems.

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