The Hypothesis Fund is a nonprofit that has an intriguing approach to funding ClimateChange and health studies. Instead of proposals, the fund will find recipients through their “scouts.”
Massachusetts Institute of Technology chemical engineer Kristala Prather is relishing the chance to present her work in person at scientific meetings now that the pandemic has eased. But starting this month, she will head to the airport with an added goal in mind: to serve as a “scout” for an unusual new funding program.
“We’re setting up a network of incredible scientists and empowering them to look for really bold ideas,” says Hypothesis Fund’s founder and CEO, Seattle entrepreneur David Sanford. Sanford knows the philanthropy world from 7 years as chief of staff to LinkedIn co-founder and billionaire Reid Hoffman, whose gift giving has included science programs. And the spark for the Hypothesis Fund, he says, goes back 20 years to when Sanford was a college student studying bone loss using mice with an atrophying limb. To trigger the atrophy, bone researchers usually cut a nerve or put the mouse’s limb in a sling. But an episode ofIt sounded crazy, but Sanford’s lab showed.
The Hypothesis Fund isn’t the first to suggest empowering a network of scientists to hand out money to their peers. Scientists in the Netherlands have, for example, but it has yet to get off the ground. It’s also just one of many programs that aim to fund high-risk science without preliminary data. But Tilghman, who has reviewed those efforts—at agencies such as the National Institutes of Health—says they are still “permeated with the fear of taking a risk.
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