A new drug to treat migraines has shown promise in a large-scale clinical trial, offering hope to people unable to use current treatment options.
FDA approves preventive migraine treatmentThe drug, ubrogepant, showed greater rates of pain and symptom relief from migraine compared to a placebo, with more than 20% of participants given the drug reporting to be pain-free within two hours and more than 34% relieved of the most bothersome symptoms linked to migraine, which include light and noise sensitivity. This is compared to 14% and 27%, respectively, from the placebo.
In the new trial, ubrogepant was tested at two doses: 25 mg and 50 mg. The lower dose had 20.7% of participants feeling pain-free after two hours and 34.1% relieved of the most bothersome symptoms. The higher dose had 21.8% and 38.9% respectively. All the findings were still lower than the symptom-relieving effect shown by triptans. "The study clearly shows the drug is effective," Silberstein said, but adds that it's"an options for patients who can't tolerate triptans.
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