A new study shows that analyzing nasal microbiota outperforms gut microbiota analysis to predict sepsis in the ICU.
The nasal microbiota of intensive care unit patients effectively distinguishes sepsis from non-septic cases and outperforms analyzing the gut microbiota to predict sepsis, according to a new study published in"These findings have implications for the development of diagnostic strategies and advancements in critical care medicine," said corresponding study author Xiaolong He, M.D., Ph.D.
In the new study, researchers recruited 157 subjects of both sexes at the affiliated hospital of Southern Medical University. They collected nasal swabs and fecal specimens from septic and non-septic patients in the ICU and Department of Respiratory and Critical Care Medicine. The scientists extracted and sequenced DNA using Illumina technology. Bioinformatics analysis, statistical processing, and machine learning techniques were used to differentiate between septic and non-septic patients.
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