mRNA-based universal flu vaccine enters clinical trials in the US

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mRNA-based universal flu vaccine enters clinical trials in the US
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The Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases (NIAID) has announced the start of a clinical trial of an experimental universal influenza vaccine.

The race to create the world's first mRNA-based universal influenza vaccine is gaining momentum.the start of a clinical trial of an experimental universal influenza vaccine.The phase 1 trial will evaluate the efficacy and immune response generated by this experimental vaccine, which is currently known as 1ssF-3928 mRNA-LNP.

There will be three study groups of ten participants each. Each participant will receive a different dose of the experimental vaccine .The groups will assist researchers in determining the best dosage. Once the optimal dosage has been determined, an additional ten participants will be vaccinated with it.’s immune response and safety. After one year of vaccination, the participants are required to attend follow-up appointments to assess the vaccine's short-term and long-term safety.

All of these issues could be addressed with the development of a universal flu vaccine. Simultaneously, it will protect recipients against various virus strains while also boosting their immunity for a longer period of time. This new type of vaccine would also eliminate the need for annual immunization.

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