Monkeypox vaccine modeling study provides road map for vaccination

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Monkeypox vaccine modeling study provides road map for vaccination
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Monkeypox vaccine modeling study provides road map for vaccination CMAJ CMAJ

Model structure. Health states and transitions. Cities, risk groups and contact networks. Note: E=exposed, H=isolating, I=infectious, R=recovered, risk=risk of monkeypox virus infection or transmission, defined by numbers of sexual partners , S=susceptible, V=vaccinated. Arrow opacity is qualitatively related to the chance of sexual contact formation from any group to another . Rate definitions can be found in Appendix 1, Section A .

Researchers modeled two hypothetical cities as interconnected networks with a combined GBMSM community size of 100,000. The team then varied the characteristics of the two cities across a range of plausible settings and simulated roll-out of 5,000 vaccine doses shortly after the first detected case of MPXV.

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