In the current spread of monkeypox among countries outside of Africa, the virus is sexually transmitted in more than 90% of cases, mostly among MSM, and can produce severe skin and systemic symptoms but is rarely fatal. EADVCongress DermTwitter
However, these data do not preclude a significant risk of nonsexual transmission, according to Català, who noted that respiratory transmission and transmission through nonsexual skin contact is well documented in endemic areas.
Typically, the incubation period of monkeypox lasts several days before the invasive period, which is commonly accompanied by systemic complaints, particularly fever, Cutaneous lesions often appear first at the site of infection, such as the genitalia, but typically spread in a secondary eruption that is pruritic and may take days to resolve, according to Català. She reported that single lesions are less common but do occur. While hundreds of lesions have been reported among cases in endemic areas, most patients had 25 lesions or fewer in the Spanish epidemic and other recent series.
"Frequently, not all the patient's lesions are in the same stage of development," said Català, who explained that disease activity and its complications, such as proctitis,, and penile edema, can take weeks to resolve. Because of the highly invasive nature of monkeypox, it is appropriate to be alert to less common manifestations, such as ocular involvement.
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