A Science analysis of the cryogenic electron microscopy structures of the full-length spike trimers of the Delta, Kappa and Gamma variants of SARSCoV2 has identified properties that might account for the Delta variant's heightened transmissibility.
). The three strains studied here show once again how different variants can use different strategies to remodel their NTD and evade host immunity. One notable implication is that the NTD function does not require specific structural elements or sequences because the surface loops, β strands in the core structure, and even some N-linked glycans can be rearranged in different ways without compromising viral infectivity.
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