Nature research article: Inheritance of paternal DNA damage by histone-mediated repair restriction
= 50 and seeded to NGM-N plates .
Synchronized embryos generated by hypochlorite treatment were hatched and arrested in M9 buffer, and then L1 worms were transferred to NGM-N plates seeded with heavy isotope labelled lysine - or normal lysine -labelled ET505. Worms were fed with labelled bacteria for two generations to reach the incorporation rate >97%, and then picked the late L4 stage worms to irradiate with ionizing radiation or mock-treated.
Staining images were taken with a Zeiss Meta 710 confocal laser scanning microscope was used. To visualize the telomeric signal,-stack pictures were processed and the number of DNA fragments was counted with Image J/Fiji v2.3.0/1.53f.The following public datasets have been re-analysed: The deletions of the hard-filtered variants of the 20220216 CeNDR 29 release
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