A comprehensive study found that viral remnants can survive for months after infection in certain people, perhaps causing some symptoms of long COVID.
Even after accounting for disease severity, whether the patients were intubated, or had underlying medical comorbidities, “there is something here that signals that patients who are persistently PCR positive have worse outcomes,” says, a neurologist at Northwestern University Feinberg School of Medicine, who led the new study.
“There are multiple leading hypotheses out there about the cause of long COVID, including viral persistence, and it may be that there are multiple pathways at play, perhaps to some varying degree in any one person,” says For their new study, the team analyzed 2,518 COVID-19 patients hospitalized in the Northwestern Medicine Healthcare system between March and August 2020. They focused on PCR tests, which are, because such tests detect genetic material from the virus and so are highly sensitive and less likely to return false negatives.
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