Created by a brilliant, well-intentioned Belgian chemist, the potent opioid now kills 20 people a day
The Public Health Agency of Canada reports that, in the first half of last year, 3,556 people died of apparent, a rate of about 20 deaths per day. In other words, on average, someone was dying somewhere in Canada nearly every hour, day and night. In the worst-hit province, British Columbia, deaths from illegal narcotics exceed those from murders, suicides, car accidents and prescription-drug overdoses combined.
He studied chemistry, founded his own company and began turning out an arsenal of successful drugs for combating everything from schizophrenia to athlete’s foot. One of them was a variation on morphine many times more powerful than the famous painkiller. The fast-acting new wonder drug calmed even the extreme pain of surgery and cancer. He called it fentanyl.
Opioids – such as morphine, named for the Greek god of dreams – have helped people ease their pain for generations. But as Paul Janssen studied the molecules that gave them their potency, he saw room for improvement., American journalist Sam Quinones describes the Belgian as “among the most fertile scientific minds of the 20th century.”
Already in use for medical anesthesia by the late 1960s, the drug was so effective that it soon spread beyond the operating theatre. Doctors prescribed it in pills, slow-release pain-relief patches applied to the skin and even a fast-acting flavoured lollipop.Alberta Law Enforcement Response Teams/The Canadian Press
Fentanyl offered the perfect solution. Because it could be cooked up in a lab by manipulating chemicals instead of refining opium, traffickers didn’t have to worry about a poppy blight in Afghanistan, a heroin eradication program in Thailand or a drug enforcement crackdown at North American ports. Today, fentanyl is no longer just a dangerous adulterant, polluting other drugs. It is the mainstream street narcotic, ubiquitous, commonplace, a market leader. People who work in safe-injection sites or drug-testing labs say they rarely see heroin anymore. It is fentanyl, fentanyl, fentanyl.
Just as other drugs are mixed into fentanyl, fentanyl is often mixed into other drugs. Weekend warriors doing lines of cocaine at a party may find they have taken fentanyl. These days, fentanyl is in everything and everything is in fentanyl.Jimmy Jeong/The Canadian Press Margaret Thompson, medical director of the Ontario, Manitoba and Nunavut Poison Centres, says fentanyl and other opioids affect the brain’s ability to detect high levels of carbon dioxide. In normal breathing, a person breathes out to expel carbon dioxide and in to get oxygen. Fenantyl disrupts that process. Breathing slows and, if the dose is big enough, eventually stops.
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