Ryan Dant was diagnosed with a rare and fatal genetic disorder as a toddler. Here's how one doctor helped him defy the odds with a new treatment.
“We were told the Ryan would probably pass away by the time he was 10 or 12 ... so for a year we did nothing but literally lay on the floor next to Ryan’s bed at night and listen to him sleep,” Mark Dant told TODAY’s Sheinelle Jones in an interview aired Tuesday.
As Ryan Dant's symptoms progressed, his"stomach became very large, his liver and spleen were growing to almost two and a half size normal, his hands started to stiffen up, he would lose balance often, would have really debilitating headaches," said Mark Dant."Things were changing physically and mentally for Ryan, too, because he began to realize that perhaps he wasn’t like the other kids who could run and play," he added.
In 1995, the Dant family flew from Texas to Los Angeles to meet Kakkis, kicking off the first chapter of a long collaboration to expand MPS I research."Meeting Ryan and Mark and Jeanne gave me an inspiration as to what this was really about. It’s not a science project. It’s a human project to save Ryan," Kakkis recalled.
"But we had great results in the first 10 patients, and ... after only a few weeks, we could see their livers and spleens were shrinking, and they started feeling better," he added.Not only did Ryan Dant beat the 10-year prediction given to him as a toddler, but he also went on to graduate from high school and college, get a job and get married. Today, Ryan Dant is 34 years old.
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