The arms race between an evolving virus and the evolving immune system is a game, with implications for COVID-19 defense and beyond. Discover more by clicking the link below. DiscoverMagazine
The last two years have created a crash course on viruses. At least, most of us have learned that when viruses emerge in a population with no defenses in place, these tiny creatures can be efficient killers and disrupt life as we know it. But what causes a virus to turn from dormant to killer? According toTel Aviv University researchers looked at a group of viruses called bacteriophages, or phages for short. Phages are viruses that attack bacteria.
Bacteria that host phages produce a peptide signal called arbitrium. Phages have special receptors that monitor these signals. Because a phage is monitoring arbitrium traffic — even when the phage is in a dormant state — it knows when nearby bacteria are infected with other phages. Game theory has been used to analyze economic and social behavior, and a great deal of biological behavior as well. You can analyze the dance between the superpowers during the Cold War in terms of game theory; how workers and employers behave in the job market; the negotiations between Russia and the rest of the world over the war in Ukraine. Or, how a virus can bring the world to its knees.
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