It’s tempting to presume a cause-and-effect relationship between two things that occur in quick succession. Even when events are completely random, we tend to see the patterns we expect to find. But researchers are not so sure Paxlovid rebound is real.
Americans who still aren’t fully vaccinated against COVID-19 probably have some immunity from a past infection. They may not be so dangerous anymore.rebound without the help of Paxlovid, scientists still have good reason to figure out whether there’s any real link.
Antiviral medications act by gumming up a pathogen’s replication machinery. But viruses rarely take that challenge lying down. They mutate constantly, and are quick to capitalize on any changes that help them overcome a drug’s defenses. Thousands of laboratory encounters between Paxlovid and the coronavirus have confirmed that the risk of inducing a Paxlovid-resistant virus is real. But in cases where patients relapsed after taking Paxlovid, scientists have found no signs that the virus has changed, Charness said.‘Night of the Living Dead’That’s actually good news, because it means Paxlovid has not yet driven the coronavirus to incorporate a mutation that allows it to short-circuit a highly effective medication.
But it still could. A medicine that weakens a virus but doesn’t finish it off puts that virus under tremendous pressure to evolve. It may behoove doctors to prescribe a longer course of the drug, or to create a more formidable cocktail by combining it with
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