The new drug for sickle cell disease
found that in 2005 alone sickle disease cost an average of $11,702 for children covered by Medicaid insurance and $14,772 for those covered by employer-sponsored insurance. Things have undoubtedly gotten more costly since then because when is the last time that you heard of healthcare having gotten cheaper over the past 15 years?
Your red blood cells are supposed to look like little doughnuts with no holes in them, so-called bi-concave discs. Here is a picture of scientist holding up a model of a red blood cell, otherwise known as an erythrocyte:... [+]The model is on the left and the scientist is on the right. Note that red blood cells don’t tend to be this large. For an erythrocyte to be larger than a man’s head, the man’s head would have to be smaller than 6 to 8 μm in diameter.
Moreover, unlike smoother disc-shaped red blood cells, these sickle-shaped ones can struggle to get through narrow blood vessels. They can stick to the inner walls of the vessels, clump together, and clog up blood vessels, creating Los Angeles-like traffic jams that impede the flow of blood to various body parts. This can result in vaso-occlusive crises. “Vaso-” means vessel, and “occlude” means stop, shut, or close.
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