Being sun smart could one day include a vaccination not unlike those currently providing millions around the world with immunity against coronavirus.
by interfering with oxidation, a chemical process which results in the loss of a molecule's electrons. For delicate structures like our DNA, this deficit can lead to chemical changes that dramatically raise the risk of cancerous mutations.High-energy radiation, including frequencies of light in the ultraviolet part of the Sun's spectrum, do a good job of knocking electrons free.
The reductase enzyme has not only been observed at elevated levels in skin cells after UV exposure, but in other tissues affected by various cancers, including melanoma. This malignant cancer of the melanocyte is the deadliest of skin cancers,Finding a way to get on top of the oxidative damage early using some of the body's own protective enzymes just might cut that death toll.
Removing the TXNRD1 gene in mice provided the research team with a way to study the enzyme's role in pigmentation and the ability of melanocytes to respond to oxidative stress resulting from exposure to ultraviolet-B radiation.
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