Epidemiological and clinical characteristics of monkeypox virus infection in cis and trans women and non-binary individuals TheLancet QMUL Sorbonne_Univ_ UofT monkeypox women nonbinary virus infection disease
By Tarun Sai LomteNov 22 2022Reviewed by Danielle Ellis, B.Sc. A recent study published in The Lancet described the clinical and epidemiologic features of infection with monkeypox virus in cisgender and transgender females and non-binary individuals.
Epidemiologic surveillance datasets have not distinguished between cis and trans women. It has been reported that, out of over 25,000 MPX cases in the United States, 3.8% occurred in cis women and 0.8% in trans women. The number of MPXV infections among females is likely unknown and probably underestimated, given the international case definitions specifying GBMSM as an at-risk group.
The spreadsheets used free-text fields and dropdown menus to allow clinicians to capture data from paper or electronic medical records. The spreadsheets primarily focused on demographic features, occupation, potential exposures, clinical findings, HIV status, early symptoms, diagnosis, concurrent sexually-transmitted infections , complications, and HIV status.
Nineteen individuals had children, including one non-binary person; two children subsequently contracted MPXV. Thirty-seven individuals had HIV, primarily trans women. Among these, 36 were on anti-retroviral therapy. Trans women had more sexual partners in the past three months than others. Mucosal lesions involving the eye, anus, vagina, or oropharynx occurred in 65 participants. Vulvar lesions were present in 42 cis women and non-binary persons assigned the female sex at birth. Perianal skin lesions were observed in 45 trans women and 17 cis women, and non-binary individuals.
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