An analysis published in BMCGeriatr reports 86% of older adults admitted with delirium and positive urinalysis, including 68% with no urinary symptoms, were treated with antibiotics for UTI. No effect was seen on faster delirium resolution.
Kappa values for antibiotic treatment , bCAM positivity on the seventh day of admission , and presence of dysuria, urgency, frequency, fever were high, suggesting excellent agreement between data abstractors. Kappa values for living arrangement, admission service and whether ED or admission diagnoses warranted antibiotic treatment were modest to good at 0.74, 0.65, and 0.64 each.
The tendency to treat asymptomatic bacteriuria in patients with delirium is consistent with findings of the recent Canadian survey of physicians by Laguë et al. [] The authors asked the respondents what the goals of antibiotic therapy were when treating bacteriuria in patients with delirium. “Infection treatment” was indicated by 83% and to “reduce the duration of delirium,” by another 65%.
We did not observe a difference in delirium resolution on the seventh day of admission between those who were treated with antibiotics compared to those given no antibiotics.
In terms of the delirious but otherwise asymptomatic cohort, we still do not have a firm conclusion whether antibiotic treatment would improve delirium resolution. However, our study suggests that such treatment does not make a large difference as a large majority – nearly 4 out of 5 patients – would have resolution of delirium on the seventh day of admission, whether given antibiotics or not.
France Dernières Nouvelles, France Actualités
Similar News:Vous pouvez également lire des articles d'actualité similaires à celui-ci que nous avons collectés auprès d'autres sources d'information.
Rita Ora gives her hair a twinkly ‘fairy’ effect with gold hair tinselRita Ora gets into the festive spirit with a glitzy new hair look featuring light-reflecting strands of gold hair tinsel: a type of semi-permanent extension going viral on TikTok
Lire la suite »
Snow in the forecast as two day weather warning issued for NI'Otherwise falling as snow with accumulations of 1 to 3 cm in places.'
Lire la suite »
Non-fatal strangulation: Man convicted under new lawThe man strangled his ex-partner just two days after the law came into effect.
Lire la suite »
Increased serum homocysteine in first episode and drug-naïve individuals with schizophrenia: sex differences and correlations with clinical symptoms - BMC PsychiatryBackground Accumulating evidence shows that homocysteine (Hcy) is implicated in the pathophysiology of schizophrenia, and plays an important role in clinical characteristics. This study evaluated the relationships between Hcy levels and clinical features in first-episode, Chinese Han, drug-naïve (FEDN) patients with schizophrenia. Methods FEDN individuals (119 with schizophrenia and 81 healthy controls matched for age, sex, education, and body mass index (BMI)) were enrolled. The serum Hcy levels were determined by enzyme cycle assay experiments. Severities of clinical symptoms were rated on the Positive and Negative Syndrome Scale (PANSS). Results FEDN individuals with schizophrenia had higher Hcy levels compared with healthy controls (F = 46.865, P 0.05). Male individuals had significantly higher serum Hcy levels than female individuals (F = 7.717, P = 0.006) after controlling for confounding factors (F = 0.759, P = 0.011). Conclusions Serum Hcy levels were increased in FEDN individuals with schizophrenia, and Hcy levels may be involved in pathophysiological mechanisms. Sex differences in Hcy levels were observed, with higher levels in male FEDN individuals compared to females.
Lire la suite »
What's triggered F1's team boss merry-go-round?F1 is well used to seeing some explosive moves in the driver market silly season, when shock events trigger a domino effect elsewhere. What is much rarer is for this kind of crazy merry-go-round to involve team principals to the extent it has this week:
Lire la suite »
What's triggered F1's team boss merry-go-round?This year's F1 silly season has shifted from driver moves to team bosses changes. NobleF1 explains what's behind all the latest announcements. ⬇️
Lire la suite »