Drug-resistant bacteria evolved on hedgehogs long before the use of antibiotics

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Drug-resistant bacteria evolved on hedgehogs long before the use of antibiotics
France Dernières Nouvelles,France Actualités
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Fungi on the animals produce natural antibiotics that may have promoted the evolution of resistance.

The team first found MRSA in hedgehogs by coincidence years ago when biologist Sophie Rasmussen, who was part of the new work and is now at the University of Oxford, approached Larsen’s team about sampling a freezer full of dead hedgehogs. Of these animals collected from Denmark,

In the new work, the scientists surveyed hedgehogs from 10 European countries and New Zealand. Workers at wildlife rescue centers swabbed the noses, skin and feet of 276 animals. MRSA was prevalent in hedgehogs in the United Kingdom, Scandinavia and the Czech Republic.MRSA, named after the gene that confers resistance, and mapped the evolutionary relationships between them by comparing mutations across their genetic instruction manuals, or genomes.

The fungi “live in a bad neighborhood,” Wright says. They have to compete with other microbes, such as, for resources and a spot to colonize on the host, and “they have to work out this arrangement where they can protect themselves.”

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