Diabetes: Why some anti-inflammatories may increase risk AskADoctor DailyHealthTips HealthcareMagic
For their study, Dr. Pofi, Prof. Tomlinson, and team recruited 16 healthy male participants. To these participants, they administered either 10- or 15-milligram doses of a glucocorticoid for 1 week.
At the end of a week of treatment, the investigators measured both regular biomarkers, such as fasting blood sugar levels and weight, and metabolic markers in the participants. "This is the first study to examine the very short-term metabolic effects of commonly prescribed doses of glucocorticoids on healthy men and indicates that, even at these lower doses, glucose metabolism is impaired, suggesting an increased risk of diabetes with continued treatment," says Dr. Pofi.
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