How highly mobile populations can skew local COVID-19 wastewater trends unlvnews jamanetworkopen
Does tourism explain the disproportionate increase in SARS-CoV-2 load observed in the Las Vegas Strip sewershed, and can this contribution be quantified to more accurately estimate COVID-19 incidence in the local community?In this cross-sectional study, the rapid onset of the Omicron BA.1 variant of concern in Las Vegas Strip wastewater was leveraged to quantify relative SARS-CoV-2 contributions from visitors and estimate Omicron prevalence in this subpopulation in late 2021 .
Samples were collected from 7 wastewater treatment plant locations that collectively serve the vast majority of southern Nevada and 1 manhole serving the southern portion of the Las Vegas Strip. With Las Vegas tourism returning to prepandemic levels in 2021, it was hypothesized that visitors were contributing a disproportionate fraction of SARS-CoV-2 RNA to the largest WWTP in southern Nevada, potentially confounding efforts to estimate COVID-19 incidence in the local community through WBE.
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