Could Crispr Flip the Switch on Insects' Resistance to Pesticides?

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Could Crispr Flip the Switch on Insects' Resistance to Pesticides?
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Many insects, like the mosquitoes that spread malaria, have evolved a tolerance to chemical sprays. What if we could reboot their genes?

: By using a gene drive to render males or females infertile, you could conceivably crash an entire population of mosquitoes.

Fredros Okumu, a parasitologist and entomologist who serves as director of science at the Ifakara Health Institute in Tanzania, says the type of gene drive tested by Bier’s team could be used as a followup to one of these other approaches by making the leftover population easier to target with pesticides. Using both types of gene drives could “counter any weaknesses of either method alone,” he says.

“A system like this would be best only in areas where certain individual gene mutations are directly linked to observable resistance features,” he says. “Still, I am personally very excited to see this.”mosquito, which transmits dengue, chikungunya, yellow fever, and Zika viruses. The pest is widespread throughout the western hemisphere, ranging from the mid-Atlantic region of the United States all the way to South America. But it wasn’t always so pervasive.

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