Two men in the United States developed encephalomyelitis after contracting monkeypox, according to a new report published by CDCgov. MedTwitter
, immunoglobulin, and penicillin. After 2 weeks, improvement in limb weakness and numbness plateaued, with continued weakness in the left leg.
Five days after symptom onset, he began experiencing bowel and bladder incontinence and progressive flaccid weakness of both legs and was hospitalized. Over the next 2 days, he developed altered mental status and obtundation, and was intubated and transferred to the intensive care unit. An MRI showed lesions on the brain and spine, and a CT revealed rectal thickening and swelling of lymph nodes in the pelvis, though the latter was thought to be related to the monkeypox infection.
His care team then initiated plasmapheresis treatment, and the patient improved substantially. After five treatments, patient B was extubated, could speak and follow commands, and his lower-extremity weakness improved. His rash healed in 5 weeks. He was given IV
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