Boston University researchers are disputing reports that they improperly tested a version of the coronavirus.
The university said researchers did not create a more dangerous strain of the original virus, and that the work was approved by an internal review committee and the Boston Public Health Commission. BU is in discussions with federal health officials about the notification process involving potentially dangerous pathogens.
The research, done by BU's National Emerging Infectious Disease Laboratories , located in Boston's South End, created a hybrid version of the SARS-CoV-2 virus by combining a protein of the omicron variant with the original strain of the virus that emerged in China in 2020. The hybrid version killed 80% of the lab mice infected, making it more deadly than the omicron variant but less deadly than the original strain.
The National Institute of Allergy and Infectious Diseases , the federal agency that oversees pathogen research and provided some funding for the BU work, requires that research on potential pandemic pathogens undergo additional scrutiny to address safety concerns. Cavallario said BU is continuing talks with NIAID about the notification requirements. Corley said because the hybrid version was not more deadly than the original virus, BU did not have to report it to federal officials.
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